Trisquel provides a good experience out of the box imo, as long as your hardware is supported and if you don’t mind the dated looking interface. I used it for a while on my corebooted laptop.
I didn’t used much any other “100% libre” distros. As much as I wanted to use it, I never managed to have Guix to run on that machine.
[edit:] to answer OP’s question, I would use a distro that ships with it.
Is it not a strange fate that we should suffer so much fear and doubt for so small a thing?