YMMV of course but I was playing Timberborn just the other day on Mint, on an Nvidia card, through Heroic. Proton seems to have been a gamechanger. I have just made my first steps into switching my daily driver myself. I may have been lucky but all the games I have wanted to play have worked so far. I also have a Steam Deck, which is what has encouraged me that it may be possible.
This may be way more in depth than you need but this guide is very comprehensive.
https://retrogamecorps.com/2022/03/13/android-emulation-starter-guide/