With 3D printers like the Open-5x or tool changers (e.g. Prusa XL) both, 5-axis simultaneous 3D-printing as well as hybrid manufacturing (additive followed up by subtractive), is more accessible than they ever were.
For those already venturing into this endeavor: What is your toolchain/software?
Currently, I finish the additive/3D print before running a second gcode for the subtractive part (contact surfaces, threads, …). This is far from an efficient and powerful process.
Did a bit of 8-axis multitool with my previous job (mostly work on a proprietary slicer), and one main takeaway was to not be afraid of editing gcode.
I would probably start with a script to merge the files and then build a basic plugin for my slicer to do the job.
I’m sure more user friendly options are around the corner!